Tired of his normal cartoon-strip routine, Garfield escapes the pages and enters into the real world. Just as he gets used to the life of being a real housecat, he learns that if he doesn't return to the strip, it will be canceled by the newspaper.
Tom & Jerry mistakenly stow away on the first manned mission to Mars and discover that we are not alone. Martians do exist! They join forces with a young Martian girl to battle asteroid fields, the Martian invasion of Earth, and an alien robot.